Collagen Wound Dressings - Biostep, Puracol, HeliPlug, Santyl

Collagen wound dressings for stalled chronic wounds - Smith & Nephew Biostep Collagen Matrix (2x2, 4x4), Medline Puracol Collagen Wound Dressing (2x2, 4 inch x 4 1/4), Integra HeliPlug (1cm x 2cm) and Helicote (1 inch square) collagen plugs, plus Smith & Nephew Collagenase Santyl ointment (15gm and 30gm tubes) for enzymatic debridement. Sterile, ships within 24 hours. Wholesale case pricing for hospitals, wound care centers and long-term care facilities.

Collagen Dressings for Stalled Chronic Wounds

Collagen wound dressings target a specific clinical situation: chronic wounds that have stalled despite standard advanced wound care. The mechanism involves collagen as a sacrificial substrate for elevated matrix metalloproteinases (MMPs) - enzymes that accumulate in chronic wound beds and degrade extracellular matrix components, preventing wound bed progression. Topically applied collagen provides a substrate for MMP activity, allowing endogenous wound bed components to support healing rather than being degraded. The catalog covers sheet collagen dressings for surface wounds, plug formats for deep wounds and tunneled sinus tracts, and Collagenase Santyl topical ointment for enzymatic debridement of necrotic wound beds.

Collagen Products Available

• Smith & Nephew Biostep Collagen Matrix - Sheet collagen dressing for chronic wounds. Available in 2x2 inch and 4x4 inch standard sizes plus additional configurations. Used for diabetic foot ulcers, venous ulcers and pressure injuries with stalled wound bed progression.
• Medline Puracol Collagen Wound Dressing - Bovine collagen wound dressing in 2x2 inch (5/bx, 10 bx/cs) and 4 inch x 4 1/4 inch (5/bx, 6 bx/cs) formats. Standard sheet collagen for chronic wound applications.
• Integra HeliPlug - Collagen plug format for deep wounds, tunneled wounds and sinus tracts. 1cm x 2cm plug size, 10 ea/bx, 5 bx/cs. The plug format addresses wound geometry that sheet collagen cannot reach.
• Integra Helicote - 1 inch square collagen wound dressing, 10/bx, 5 bx/cs. Small-format collagen for focal wound application.
• Smith & Nephew Collagenase Santyl Ointment - Topical enzymatic debridement ointment, available in 15gm and 30gm tube formats. Used for chemical debridement of necrotic tissue, eschar and slough in chronic wounds where surgical debridement is not appropriate.

Collagen Formats by Wound Geometry

When Collagen Dressings Are Used

Collagen dressings are not first-line wound care - they are specialty products used in defined clinical situations after standard advanced wound care has not produced wound bed progression. The typical clinical decision point is a chronic wound that has been managed with appropriate primary dressings (foam, alginate, silver/antimicrobial as indicated) for 2-4 weeks without measurable wound bed improvement. At that point, collagen dressings are introduced to address the elevated MMP environment that may be preventing progression. Clinical applications include diabetic foot ulcers with adequate vascular supply, chronic venous leg ulcers, pressure injuries with viable wound beds, and complex surgical wounds with delayed closure.

Collagenase Santyl Enzymatic Debridement

Collagenase Santyl is functionally different from the other collagen products in this subcategory - it is a topical enzymatic debridement ointment rather than a wound dressing. The active ingredient (collagenase clostridium histolyticum) selectively digests denatured collagen in necrotic tissue without damaging viable wound bed. Used as an alternative or adjunct to surgical debridement in chronic wounds where serial sharp debridement is not appropriate, in patient populations where surgical debridement is contraindicated, or in wound care settings (outpatient clinics, home health) where surgical debridement equipment and procedures are not available. Available in 15gm tube for short-course use and 30gm tube for extended debridement courses.

Collagen wound dressings and Collagenase Santyl together represent the catalog options for managing stalled chronic wounds and enzymatic debridement. The Biostep and Puracol sheet products, HeliPlug plug format and Santyl ointment cover the full clinical range. Order at the best Wholesale Prices with MAP Medical.